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Posted on 2008-09-09 21:15:34

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"Gilead Announces 48-Week Data Evaluating Switching From Combivir(R ..." posted by ~Ray
Posted on 2007-12-20 23:16:28

Gilead Sciences. Inc. (Nasdaq: GILD) announced 48- week data from a Phase III clinical trial evaluating virologically-suppressed patients with HIV who switched from treatment with twice-daily Combivir® (lamivudine/zidovudine) to treatment with Gilead’s once-daily Truvada® (emtricitabine and tenofovir disoproxil fumarate) as part of their combination drug therapy. In the SWEET (Simplification With Easier Emtricitabine and Tenofovir) chew over patients who switched from Combivir to Truvada both in combination with once-daily Sustiva® (efavirenz) experienced improvements in a equal in be of treatment-related side forces. Patients in both study arms maintained virological suppression at 48 weeks. The data were presented at the 11th European AIDS Conference (EACS) held October 24-27 in Madrid. Spain. “As HIV patients be longer and remain on therapy for extended periods of measure the long-term side effect outline of is increasingly more important,” said Martin Fisher. MD. Brighton and Sussex University Hospitals. Brighton. United Kingdom and the principal investigator for the SWEET study. “Data from this study indicate that patients on long-term Combivir therapy without clinical lipoatrophy may benefit from switching to Truvada as virological control can be maintained and limb fat loss and recovery may be improved. These data support the new EACS 2007 guidelines regarding proactive switching.” New European HIV treatment guidelines issued this week at EACS list Truvada among the recommended components of a first-line treatment regimen for antiretroviral naïve patients. Combivir previously recommended as a first-line treatment option is now listed as an choice usage option. In the United States the components of Truvada and Sustiva are available in a fixed-dose combination tablet called Atripla® (efavirenz 600mg / emtricitabine 200mg / tenofovir disoproxil fumarate 300 mg). Atripla is currently the first and only once-daily single tablet regimen approved for the treatment of HIV-1 infection in adults in the United States for use either as stand-alone therapy or in combination with other antiretroviral agents. On October 18. 2007 the Committee for Medicinal Products for Human Use (CHMP) of the European Medicines Agency (EMEA) recommended that Atripla be approved for use in the European Union. A conclusive decision on Atripla by the European Commission is expected by the end of the year. SWEET was a 48-week multicenter.





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"How to Beat the High Cost of Dental Insurance" posted by ~Ray
Posted on 2007-11-23 15:09:32

The cost of dental insurance has gone through the cover in recent years. It’s now a proven statistic that approximately 70% of American have no dental coverage at all for the create that of this. However the most disturbing thing about this is that most dental insurance plans really don’t provide much coverage. Many people aren’t change surface aware of what they’re buying until they get to the dentist and undergo their claim denied because the procedure that they need to undergo done is considered to be pre-existing and dental insurance won’t adjoin anything that’s pre-existing. That means that if your spouse or daughter is in hurt right now and you don’t already have insurance you are on your own. The beat way to defeat the high cost of dental insurance is to join what’s called a reject dental plan. Many of these discount plans offer savings of as much as 60% off on most study dental care as come up as preventive care such as cleanings x-rays etc. Since reject plans are not an insurance policy you can be seen for any reason pre-existing or not. There aren’t any exclusions no age limits no co-pays no headaches. This is how discount plans bring home the bacon. Find a dentist in your area that is a of the allow reticulated. Join the plan by the low annual fee. This is usually for that which is less than $100.00 for an individual which is much less than insurance. Within 1-3 days you can see a participating dentist. Once you get your activation notice plainly make an appointment get a check-up and x-rays verify what needs to be done and what you can afford to pay that day and then get the bring home the bacon done. It’s just that easy. If you’ve been looking for affordable dental I can tell you that it just doesn’t if you consider what you’re actually getting for your money. I back up you to be at both dental assurance (make sure to look at the “Exclusions”) and discount dental plans. I think you’ll be shocked at what you find. XHTML: You can use these tags: <a href="" title=""> <abbr call=""> <acronym call=""> <b> <blockquote cite=""> <code> <em> <i> <strike> <strong>





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"How to Beat the High Cost of Dental Insurance" posted by ~Ray
Posted on 2007-11-23 14:51:20

The cost of dental insurance has gone through the roof in recent years. It’s now a proven statistic that approximately 70% of American have no dental coverage at all for the cause that of this. However the most disturbing thing about this is that most dental insurance plans really don’t provide much coverage. Many people aren’t even aware of what they’re buying until they get to the dentist and have their claim denied because the procedure that they need to have done is considered to be pre-existing and dental insurance won’t cover anything that’s pre-existing. That means that if your spouse or daughter is in hurt right now and you don’t already have insurance you are on your own. The beat way to beat the high cost of dental insurance is to connect what’s called a reject dental plan. Many of these discount plans offer savings of as much as 60% off on most major dental compassionate as well as preventive compassionate such as cleanings x-rays etc. Since reject plans are not an insurance policy you can be seen for any reason pre-existing or not. There aren’t any exclusions no age limits no co-pays no headaches. This is how discount plans work. Find a dentist in your area that is a of the allow reticulated. connect the plan by the low annual fee. This is usually for that which is less than $100.00 for an individual which is much less than insurance. Within 1-3 days you can see a participating dentist. Once you get your activation notice plainly make an appointment get a check-up and x-rays verify what needs to be done and what you can afford to pay that day and then get the bring home the bacon done. It’s just that easy. If you’ve been looking for affordable dental I can tell you that it just doesn’t if you consider what you’re actually getting for your money. I encourage you to look at both dental assurance (make sure to be at the “Exclusions”) and discount dental plans. I think you’ll be shocked at what you sight. XHTML: You can use these tags: <a href="" call=""> <abbr title=""> <acronym title=""> <b> <blockquote cite=""> <code> <em> <i> <strike> <strong>





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"How to Beat the High Cost of Dental Insurance" posted by ~Ray
Posted on 2007-11-23 14:44:33

The cost of dental insurance has gone through the roof in recent years. It’s now a proven statistic that approximately 70% of American have no dental coverage at all for the cause that of this. However the most disturbing thing about this is that most dental insurance plans really don’t provide much coverage. Many people aren’t change surface aware of what they’re buying until they get to the dentist and have their claim denied because the procedure that they be to have done is considered to be pre-existing and dental insurance won’t cover anything that’s pre-existing. That means that if your spouse or daughter is in pain alter now and you don’t already undergo insurance you are on your own. The best way to beat the high cost of dental insurance is to join what’s called a discount dental plan. Many of these reject plans offer savings of as much as 60% off on most major dental care as well as preventive care such as cleanings x-rays etc. Since discount plans are not an insurance policy you can be seen for any reason pre-existing or not. There aren’t any exclusions no age limits no co-pays no headaches. This is how discount plans work. Find a dentist in your area that is a of the allow reticulated. connect the plan by the low annual fee. This is usually for that which is less than $100.00 for an individual which is much less than insurance. Within 1-3 days you can see a participating dentist. Once you get your activation notice plainly make an appointment get a check-up and x-rays affirm what needs to be done and what you can afford to pay that day and then get the bring home the bacon done. It’s just that easy. If you’ve been looking for affordable dental I can tell you that it just doesn’t if you believe what you’re actually getting for your money. I encourage you to look at both dental assurance (alter sure to be at the “Exclusions”) and discount dental plans. I think you’ll be shocked at what you sight. XHTML: You can use these tags: <a href="" title=""> <abbr title=""> <acronym title=""> <b> <blockquote have in mind=""> <code> <em> <i> <strike> <strong>





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"Book musings" posted by ~Ray
Posted on 2007-11-07 15:43:21

I’ve been asked to “swing by the mall” before – you know to pick up something from the jewelry/butane-lighter/cell-phone-accessory kiosk usually managed by a guy who fluently speaks seven languages plus a little bit of broken English. And whoever asks this favor of you fails to have in mind the location of this substandard merchandise booth. conceive of the typical design of a mall: usually three or four different pathways or branches that arbitrarily shoot in various directions. There is no real organization to a mall’s coordinate and in many cases the floor plan ends up taking the shape of a guy bending over and holding his ankles. Maybe that’s a bit of a stretch but it’s fun to create by mental act seeing that on a blueprint. And imagine if you had to draw an anus on this blueprint. Really that’s where the shit-trinket kiosk will be located: alter in the asshole of the mall. There is no practical displace to park that will make your move quicker. You can either lay in the lot closest to the mall’s ankles where there are no spots within a quarter mile of the appeal or you can just lay at the other end of the mall next to the department store that closed drink six years ago and was abandoned because the mall hasn’t been updated in several decades. Either way there is no “swinging by” the mall to pick up anything. There has been absolutely no time in my life when the mall was enjoyable to me. Not even when I was kid when I could go into that one crappy toy hold on that sold a small quantity of a variety of everything I dislike. For most children the mall is associated with the chore of clothes shopping and trying on everything that’s on sale. Like parkas in July. And this is the root of the problem. When parents act their kids to the mall it’s an errand – or more of a mission. That mission is to sight educate clothes buy a new pair of trendy sneakers so he’ll “fit in,” and make several selfish side trips to look at purses and cheap cell telecommunicate accessories. The child is dragged around against his will and the simple mind of a 9-year-old begins to alter visions of the mall into images of what hell might really be like. If you’re desire me and you retain that vision of the mall all the way to adulthood you develop a deep hatred that chills your very soul every time you undergo to go there. Hell cannot be hell without demons. Lately. I’ve come to realize that it’s not just the mall that I hate; it’s the inhabitants of the mall in all their diverse stereotype glory. But the only way to explain why I dislike most mall patrons is to tell you a little bit about each of the main types. I realize that over the decades this style of gratify has been exhausted and probably even done way exceed by various outdated comedians. But it’s necessary. So go grab a cup of coffee or pop some amphetamines to help you get through it. – this abortion that forgot to take place can be open shopping unsupervised at all of the trendy stores trying on shorter and sluttier replacements for her already-over-the-top-whorish panty-shorts. All this is done between sending text messages on her cell phone of course. The only thing worse than the 12-year-old harlot is her parents. – color shoes color pants black shirt beige skin. Cynical T-shirt Boy is the goth who dares to be a conformist by going to the mall. But not without his douche-bag T-shirt that says “I’m glad you aren’t talking to me” or some other phrase that desperately cries out for attention via reverse psychology. All he really needs is a hug. – Is that a shopping enumerate in your pocket urban youth assort? No it’s merely a merchandise tag hanging from the shirt you’re wearing. Forgot to cut it off. I guess. Also forgot to end putting on your pants apparently. And why do I never see you carrying any shopping bags? There’s something fishy going on with the urban youth of – the well-dressed yuppie who makes a inform of having a loud conversation on his cell phone the entire measure he’s at the mall. It’s important to him that everyone knows he is conducting serious business and is not there to obtain among you middle-class ants; he’s a big broach. He is the store manager of Taco Bell. – skate fanatics don’t actually enter the building but they’ve discovered that the mall has plenty of steps railings and change state cover on which they can infuriate me by defying Darwinism. Sk8er Kids somehow be alive despite the plethora of injuries they sustain. You can audibly detect a Sk8er Kid in the vicinity with a distinct series of onomatopoeias: displace! POW! – followed by – “Oh God it – he lurks in every corner taking one shady sales job after another. Today he’s trying to sell you those over-priced electronic moving photos; tomorrow who knows? He might be in a cell phone store trying to sell landlines or demonstrating a set of knives to meet a sales quota as stated in the contact he blindly signed. No matter what he might.





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